Polyphenols Applications News - Polyphenols Applications World Congress

From Polyphenol Metabolism to Precision Nutrition: Advancing Translation to Human Health

2026-07-21T09:45:00+00:00

Why Do We Respond Differently to Polyphenols? Toward Precision Nutrition. We are pleased to welcome Prof. Pedro Mena Parreño from the University of Parma, Italy, as a speaker at Polyphenols Applications 2026.

He will present: From Polyphenol Metabolism to Precision Nutrition: Advancing Translation to Human Health

One of the key questions in polyphenol science is no longer only what do polyphenols do? but why do individuals respond differently?

Prof. Mena will discuss how inter individual variability in polyphenol metabolism and biological response may shape effects on obesity and cardiometabolic health. His lecture will highlight findings from the Oral Polyphenol Challenge Test, a large acute intervention study in 300 subjects, which identified distinct metabotypes linked to dietary habits, microbial composition, genetic background, and cardiometabolic traits.

He will also discuss how multi omics and advanced analytical platforms are helping to translate polyphenol science into precision nutrition, including preliminary results from the PRE CARE DIET randomized controlled trial.

This talk brings a strategic perspective to Polyphenols Applications 2026: moving from polyphenol intake toward personalized, sustainable, and clinically relevant nutrition strategies.

Join us in Málaga for Polyphenols Applications 2026, where science, nutrition, and innovation will meet to rethink the future of prevention.

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Can Animal Nutrition Reveal the True Biofunctionality of Polyphenols for Human Health?

2026-07-21T09:40:00+00:00

We are pleased to welcome Prof. Dr. Katrin Giller from the University of Hohenheim, Germany as a speaker at Polyphenols Applications 2026.

She will present: Specific Biofunctionality of Polyphenols: Insights from Ruminant and Human Nutrition

Polyphenols are increasingly recognized as modulators of nutrient utilization, metabolic efficiency, oxidative stress, and immune function. But are their effects universal, or highly species-specific?

Using tannins as model compounds, Prof. Giller will explore how polyphenols influence protein utilization, methane reduction, fatty acid transfer, and environmental sustainability in ruminants, while drawing important parallels with human nutrition and cardiometabolic health.

Her lecture will address a strategic question for the future of the field:

Which findings on polyphenols can truly be translated from animal models to human health and where should caution prevail?

This talk brings a valuable scientific and translational perspective to Polyphenols Applications 2026.

Join us in Málaga for Polyphenols Applications 2026, where science, nutrition, and innovation will meet to rethink the future of prevention.

For more information - LinkedIn

Is the GUT the Place where Polyphenols Become Biologically Meaningful?

2026-07-21T09:30:00+00:00

We are pleased to welcome Professor Kieran Tuohy from the University of Leeds, UK, as a featured speaker at Polyphenols Applications 2026.

Professor Tuohy will present: Polyphenols, Fibers and Microbial Metabolites: Decoding the Gut Dialogue

Professor Tuohy is internationally recognized for his work on gut microbiology, nutrition, and the interaction between dietary polyphenols, fibers, and the gut microbiome.

Professor Tuohy's lecture will address a central question for the field: How does microbial metabolism transform polyphenols and fibers into bioactive signals that influence inflammation, gut barrier function, cardiometabolic health, and systemic physiology?

This topic is highly aligned with the Session Microbiome Dialogue, where the congress will explore the polyphenol–fiber–microbiome axis and its implications for precision nutrition and future health strategies.

Join us in Málaga for Polyphenols Applications 2026, where science, nutrition, and innovation will meet to rethink the future of prevention.

For more information - LinkedIn

Can we rethink polyphenol intake for the modern lifestyle?

2026-07-21T09:25:00+00:00

For years, we have focused on how many polyphenols we consume. Perhaps the more important question is: How much actually reaches our body after food processing, storage, and digestion?

At Texas A&M University, USA, Prof. Bhimu Patil and colleagues present a compelling new perspective on precision nutrition.

Their work shows that preserving polyphenols is not simply about choosing the right foods; it is also about choosing the right processing technologies.

Among their findings:

Frozen blueberries can contain anthocyanin levels comparable to, or even higher than, fresh berries.
Minimally processed tomato juices contained up to six times more polyphenols than ultra-processed products.
A new UHPLC-DAD analytical method enables the rapid quantification of 31 major polyphenols in just 15 minutes, opening new possibilities for food quality assessment and research.
Their research also highlights the biological potential of citrus flavonoids and the need to combine advanced analytical methods with clinical evidence to move toward precision nutrition.

This work reminds us that the health benefits of polyphenols depend not only on the plant itself, but also on how foods are processed, preserved, and delivered.

We are delighted to welcome Prof. Bhimu S. Patil from Texas A&M University, USA, as a plenary speaker at the 19th World Congress on Polyphenols Applications, where he will present this exciting vision of the future of polyphenol science and precision nutrition.

Join us in Málaga for Polyphenols Applications 2026, where science, nutrition, and innovation will meet to rethink the future of prevention.

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Can Polyphenols Protect the Diabetic Retina Before It Is Too Late?

2026-07-21T09:20:00+00:00

We are pleased to announce that Dr. Ángel Luis Ortega, from the University of Valencia, Spain, will join Polyphenols Applications 2026 as a speaker.

His lecture, “Can Polyphenols Delay Diabetic Complications? Pterostilbene as a Translational Model in Retinal Health,” will explore how polyphenols may contribute to the prevention of chronic metabolic complications, with a particular focus on diabetic retinopathy.

Dr. Ortega’s work highlights pterostilbene, a natural polyphenol related to resveratrol, and its potential role in protecting retinal tissues against oxidative stress, inflammation, and vascular damage associated with diabetes.

This presentation will bring an important translational perspective to the congress, connecting polyphenols, metabolic disease, microvascular dysfunction, and retinal health.

Join us in Málaga for Polyphenols Applications 2026, where science, nutrition, and innovation will meet to rethink the future of prevention.

For more information - LinkedIn

Can our GUT Microbiome Learn to use Polyphenols?

2026-07-21T09:15:00+00:00

We are delighted to welcome Stephanie Wilson as an invited speaker at Polyphenols Applications 2026, taking place on October 8–9, 2026, in Málaga, Spain.

Dr. Wilson's research explores a fascinating question: can a polyphenol-rich diet shape not only the composition of the gut microbiome, but also its ability to metabolize polyphenols?

Drawing on data from 313 healthy adults, her team combined dietary assessments with metagenomic sequencing to show that people who consume a more diverse range of dietary polyphenols have a greater abundance and diversity of microbial genes involved in polyphenol metabolism. The findings suggest that regular exposure to polyphenol-rich foods may enhance the functional capacity of the gut microbiome.

Her presentation, "How the Gut Microbiome Learns to Use Polyphenols: New Insights from Human Studies," will offer fresh perspectives on the dynamic relationship between diet, the microbiome, and human health.
We look forward to welcoming Dr. Wilson to Málaga and to the stimulating discussions her work will inspire.

Join us in Málaga for Polyphenols Applications 2026, where science, nutrition, and innovation will meet to rethink the future of prevention.

For more information - LinkedIn

Can dietary polyphenols become part of the next strategy for healthy aging?

2026-07-21T09:10:00+00:00

We are pleased to welcome Prof. Sergio Davinelli from the Università degli Studi del Molise, Italy, as a speaker at Polyphenols Applications 2026.

Prof. Sergio Davinelli will present: Dietary Polyphenols as Geroprotective Compounds: From Nutrition to Healthy Aging

His lecture will explore how polyphenol rich compounds may contribute to prevention strategies, metabolic resilience, and protection against age related decline. This perspective is particularly important as polyphenols are increasingly studied not only as antioxidants, but as modulators of inflammation, cellular senescence, microbiota, and longevity pathways.

At a time when healthy aging is becoming a global priority, this talk will address a strategic question:

How can nutrition based interventions help extend healthspan, not only lifespan?

Join us in Málaga for Polyphenols Applications 2026, where science, nutrition, and innovation will meet to rethink the future of prevention.

For more information - LinkedIn

Can Polyphenols Help Livestock Become Part of the Climate Solution?

2026-07-21T09:00:00+00:00

Can polyphenols help reduce methane emissions from ruminants without compromising animal health and food quality? This question will be addressed at Polyphenols Applications 2026 by Dr. Maria Hayes, from the Teagasc Food Research Centre, Ireland.

She will present:
Reducing Methane Emissions with Polyphenols: New Strategies for Sustainable Animal Production

Her lecture will focus on the potential of seaweed extracts rich in polyphenols and other bioactives to reduce methane emissions from cows and sheep, based on work carried out within the SeaSolutions project.

The challenge is strategic: how can we reduce greenhouse gas emissions from ruminant production while maintaining animal performance, health, and the quality of milk and meat?

This talk brings an important agricultural and sustainability dimension to Polyphenols Applications 2026, showing how polyphenol research can move beyond human nutrition and contribute to future food systems.

Join us in Málaga and elevate your conference experience at ILUNION Málaga.

Call for Abstracts and Innovation Submissions

2026-01-21T14:12:00+00:00

We are pleased to announce that the Call for Abstracts and Innovation Submissions is now open for Polyphenols Applications 2026.

Polyphenols Applications 2025: Concluding Remarks

2026-01-20T16:24:00+00:00

Rethinking Prevention: How Polyphenols Are Reshaping Health and Innovation.

Over these two days we've seen something very clear. Polyphenols are no longer just a scientific curiosity. They are becoming a strategic tool for health innovation and sustainability.

Abstracts book of Polyphenols 2025 Congress

2026-01-16T14:09:00+00:00

The Polyphenols Applications 2025 Abstracts Book - containing all 105+ major, short talks and poster presentations - is now available.

Practical Information & Final Agenda of Polyphenols Applications 2025

2025-09-30T11:07:00+00:00

Dear Speakers, Chairpersons, and Attendees,

We look forward to meeting you all on October 2-3 at Polyphenols World Congress 2025. We remind you of the important information below regarding your participation.

1. Congress Venue
Corinthia Palace
De Paule Avenue, BZN 9023 San Anton, Malta

Venue Details

2.⁠ ⁠Online Participation
Online Attendees will receive a Zoom Link 2 days before the meeting starts.

3.⁠ ⁠Badge Pick Up
You can pick up your badges upon your first entry, on Thursday, October 2, starting at 8 a.m.
Please make sure to wear it throughout the congress.

4.⁠ ⁠Final Program
You can find here the Polyphenols World Congress 2025.

5.⁠ ⁠Short Oral Presenters Guidelines
1. Kindly note down the updated timing of your presentation. Please make sure to abide by the duration of your talk (8-minute presentation + 2 minutes for discussion).
2. Make sure to bring your presentation with you on a flash drive on-site.
3. Please note that all presentations will be collected by the technician, and no presentation via their own laptop will be accepted.
4. Note: PowerPoint presentation’s ratio: 4:3.

6.⁠ ⁠Posters List & Guidelines
Please find the accepted poster list below. Check your poster number and the day of your presentation. If you are joining in person, make sure to print your poster and bring it with you (A1 vertical format). Posters will be presented during the coffee breaks & lunch break. You will have to hang the poster according to its number. Please note down the number of your poster. You can also send us your PDF poster.

ACCEPTED POSTER LIST

7. Dinner

The Polyphenols Applications 2025 dinner will be held on Thursday, October 2, at the Corinthia Palace Hotel in Malta. You can join this dinner from 8:00 PM. It is a perfect opportunity to have an interactive discussion.
You can participate in the dinner by registering here.

8. ⁠Contact For Urgent Matters

If you have any questions, you can contact us via email [email protected]">[email protected]

If your abstract or talk is missing, or if your name and title need correction, please contact us.

We look forward to meeting you all.

Iprona and Polyphenols Applications Launch Global Call to Advance Robust, Reproducible Polyphenol Research

2025-09-29T14:42:48+00:00

At the 18th World Congress on Polyphenols Applications, Iprona and Polyphenols Applications announce a global call to action, inviting researchers to strengthen the quality and reproducibility of polyphenol science.

Through this initiative, ElderCraft®, a polyphenol-standardised European black elderberry (Sambucus nigra) water extract, is now available at no cost to qualified academic and clinical research groups worldwide.

ElderCraft® is a polyphenol and anthocyanin-rich extract, sourced exclusively from Austrian elderberries and produced using gentle ultrafiltration to preserve the natural profile of bioactive compounds. Each batch comes with Certificates of Analysis (CoAs), HPLC fingerprints, and stability data, ensuring traceability, batch-to-batch consistency, and study-ready analytics.

“Robust, comparable data begins with robust, comparable materials,” said Dr. Stephan Plattner, Scientific Director, Health & Nutrition Ingredients at iprona. “By sharing ElderCraft® with the research community, we aim to reduce study-to-study variability, enable stronger meta-analyses, and help unlock clearer dose–response and subgroup insights in polyphenol science.”

Polyphenols Applications 2025, organiser of the World Congress on Polyphenols Applications, fully supports this effort and encourages researchers across mechanistic, preclinical, and clinical fields to integrate highly characterised, standardised polyphenol extracts into their work.

Why It Matters

Improved reproducibility: Tight batch tolerances and full analytics reduce variability between studies.
Meta-analysis ready: Standardisation enables stronger dose–response and subgroup evaluation.
Translational relevance: ElderCraft® is already used in global consumer products, connecting research to real-world impact.
Compliance support: Full traceability and documented quality facilitate ethical and regulatory submissions.

Research areas include immune function, gut microbiome modulation, viral defence, cardiometabolic health, cognitive performance, healthy ageing, and energy metabolism.

Request research material Link:
https://www.craft-ingredients.info/references/eldercraft-research-material-request

Contact
Scientific queries/material: Dr. Stephan Plattner (Scientific Director, Health & Nutrition Ingredients, Iprona Lana) – [email protected]">[email protected]

About ElderCraft®
https://www.craft-ingredients.info/our-ingredients/eldercraft

The 18th World Congress on Polyphenols Applications is the global forum where polyphenol science meets clinical translation. By joining forces, iprona and Polyphenols Applications aim to accelerate high-quality, reproducible studies that advance the field and clarify the health potential of polyphenols.

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About iprona

Iprona is a global leader in fruit processing and bioactive ingredient development. With decades of expertise in polyphenol-rich extracts, iprona supports science-driven innovation and the creation of evidence-based health applications.

About Polyphenols Applications

Polyphenols Applications is an international scientific platform and organiser of the World Congress on Polyphenols Applications, fostering collaboration among researchers, clinicians, and industry to advance understanding and application of polyphenols in health and disease.

www.polyphenols-site.com

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Disclosure: ElderCraft® is provided by iprona for research use only. This announcement is issued in collaboration with Polyphenols Applications and supported by iprona.

Join the global leaders shaping the future of nutrition and healthy ageing!

2025-09-29T12:29:00+00:00

Polyphenols: From Powerful Antioxidants to Game Changers in Modern Nutrition

We are thrilled to announce that Malta will host more than 200 international experts from 27 countries for Polyphenols Applications 2025, the leading global meeting on polyphenol science, health, and innovation.

Why it matters
Polyphenols are no longer just antioxidants, they are shaping modern nutrition, healthy ageing, microbiota balance, brain and cardiovascular health, and driving the next generation of functional foods, nutraceuticals, cosmetics, and therapeutics.

Program highlights
✔️ Polyphenols & Microbiota
✔️ Polyphenols & Ageing / Mitochondrial resilience
✔️ Clinical & Translational Research
✔️ Food, Cosmetic & Pharma Innovations

This event is supported by Iprona.

A unique platform bringing together academia, clinicians, nutrition experts, start-ups, and industry leaders to accelerate translation from science to market.

View the full program: Download Program PDF

Join us in Malta — Registration & abstract submissions are now open! Register here

Special Issue on Polyphenols in Molecular Nutrition & Food Research Journal is published

2025-09-10T09:34:00+00:00

Molecular Nutrition & Food Research published a Special Issue following the 17th Polyphenols Applications 2024 World Congress, which took place in Milan from September 19th to 20th, 2024.

The special issue focuses on:

Polyphenols in Health and Disease;
Polyphenols, Microbiota and Metabolites;
Polyphenols and Food Research;
Clinical Applications and Future Directions.

The special issue will be gratefully guest-edited by Juan Carlos Espin (CEBAS-CSIC, Murcia, Spain) & Cristian Del Bo' (University of Milan, Italy), most well-known for their high-standard research in the field.
Juan Carlos Espin (CEBAS-CSIC, Murcia, Spain)	Cristian Del Bo' (University of Milan, Italy)

Follow this link to check out the Special Issue.

Keynote Speech: Prof. Bhimu Patil

2025-05-21T08:20:00+00:00

Prof. Bhimu Patil, a Regents Professor and Inaugural Leonard Pike University Professor at Texas A&M University, USA, will give a Keynote speech entitled 'The Preventive Power of Plant Polyphenols: Scientific Advances from Fruits and Vegetables' at the 18th World Congress on Polyphenols Applications 2025, which will be held in Malta on 2-3 October.

Keynote Speech: Prof. Mario Ferruzzi

2025-04-23T12:12:52+00:00

Prof. Mario Ferruzzi, Dean of the College of Agriculture and Life Sciences at Virginia Tech, USA, will give a Keynote speech entitled 'The Beautiful Complexity of Dietary Polyphenols: Our tools for Addressing Challenges across Food, Nutrition and Health Domains' at the 18th World Congress on Polyphenols Applications 2025, which will be held in Malta on 2-3 October.

Reactions of Polyphenols: Recent Progress in Chemical and Enzymatic Conversions - New Session at Polyphenols

2025-02-14T12:49:27+00:00

The 18th World Congress on Polyphenols Applications 2025 will introduce a new session: “Reactions of Polyphenols: Recent Advances in Chemical and Enzymatic Conversions”, moderated by Prof. Andreas Schieber, Vice-President of Polyphenols Applications, University of Bonn, Germany.

Best Scientific Contribution Award for Advancing Polyphenols in Oncotherapy at Polyphenols Applications 2024

2024-09-30T14:01:08+00:00

Prof. José M. Estrela from the University of Valencia has received the Best Scientific Contribution Award at Polyphenols Applications 2024 for his research on “Polyphenols in Oncotherapy: Moving Forward from the Bench to Clinical Applications.” His work addresses the challenge of polyphenols' poor bioavailability in vivo and their potential in cancer treatment.

While polyphenols demonstrate significant anti-cancer effects in preclinical studies—such as inducing cell cycle arrest and inhibiting angiogenesis—issues like limited absorption hinder their clinical application. Prof. Estrela highlights innovative delivery systems, including nanoparticles and liposomes, to enhance bioavailability and efficacy.

About Prof. Estrella

As a professor of physiology and director of the Cell Pathophysiology Unit at the University of Valencia, as well as research director at Scientia BioTech, Prof. Estrela is pioneering new anti-cancer strategies that integrate polyphenols for improved therapeutic outcomes. Congratulations to Prof. Estrela on this well-deserved recognition!

Molecular Mechanisms of Flavan-3-ol Degradation: Best Short Oral Presentation Award at Polyphenols Applications 2024

2024-09-30T13:50:45+00:00

Pascale Mosoni of INRAE has won the Best Short Oral Presentation Award at Polyphenols Applications 2024 for her research on “The Molecular Basis of the Degradation of Flavan-3-ols by the Human Gut Bacterium Eggerthella Lenta.”

Dr. Mosoni's presentation delved into how Eggerthella lenta metabolizes flavan-3-ols—polyphenols known for their cardiovascular benefits—into bioactive compounds in the gut. By identifying ten key genes responsible for this metabolic process through a transcriptomic approach, Dr. Mosoni's work has revealed that 27% of individuals lack the ability to convert these polyphenols, raising important questions about cardiovascular risk factors.

About Dr. Mosoni

Dr. Mosoni is a microbiologist in MEDIS (Microbiology, Digestive Environment & Health) laboratory at INRAE. Her research activities are currently focusing on the metabolism/degradation of dietary fibers and polyphenols by the human gut microbiota in order to better understand the effects of these plant dietary components on health through the action of the microbiota. The approaches used involve the isolation of anaerobic microorganisms contributing to these metabolic pathways and characterize their function (genes, enzymes, metabolites) and role in health. Her aim is to discover new generation pre- pro- syn-biotics, or effective bioactive molecules (postbiotics) to be used in preventive nutritional strategies.

Group Berkem Wins Second Best Poster Presentation Award at Polyphenols Applications 2024

2024-09-30T13:50:33+00:00

Congratulations to Jean-Paul Joseleau from Groupe Berkem for winning the Best Poster Presentation Award (2) at Polyphenols Applications 2024! His innovative research on “BERGENOL®, A Novel Vegetal Virucidal Agent for Hand Sanitizer Formulations” introduced a breakthrough in plant-based, alcohol-free sanitizers.

Derived from Vitis vinifera, Bergenol® demonstrated outstanding virucidal activity against a range of viruses, including those from the coronavirus and adenovirus families.

This recognition highlights the growing importance of natural, sustainable solutions in human hygiene, offering a safer alternative to chemical-based disinfectants. Well done to Dr. Joseleau for this achievement!

About Group Berkem

Groupe Berkem is a European Chemical manufacturer actively involved in the ecological transition. One of Groupe Berkem’s expertise is to use vegetal extracts in a wide range of sectors. It provides innovative and sustainable solutions to develop active ingredients for cosmetics and nutraceuticals, wood protection, disinfectants and human hygiene…

Nestlé Research Wins First Best Poster Presentation at Polyphenols Applications 2024

2024-09-30T13:50:29+00:00

Dr. Laure Poquet of Nestlé Research has been awarded the Best Poster Presentation (1) at Polyphenols Applications 2024 for her outstanding research on oleuropein metabolites.

Her poster, “Oleuropein Metabolites Are Biologically Active as Mitochondrial Calcium Activators at the Concentration Measured in Human Plasma,” highlighted the bioactivity of these metabolites derived from olive leaf extracts.

The study demonstrated that, at concentrations measurable in human plasma, these metabolites can activate mitochondrial calcium, leading to enhanced energy metabolism in muscle cells.

A new study was performed by Nestlé scientists to understand how the polyphenols from olive leaf extract can boost muscle energy. The main natural polyphenolic compound of this extract is oleuropein. Its metabolites circulating in plasma after intake were detected and quantified using a validated LC-MS/MS method. Their potential biological activities as mitochondrial activators were tested in vitro, at the circulating concentrations. The results showed that, although the level of oleuropein was low, its metabolites are biologically active in skeletal muscle cells and reach a total concentration in human blood sufficient to activate mitochondrial energy metabolism via mitochondrial Ca2+ activation.

This achievement marks a significant step in understanding the role of oleuropein in improving muscle function and supporting healthy aging. Congratulations to Dr. Poquet on this well-deserved recognition!

Videos On-Demand now Available

2024-09-13T11:10:43+00:00

All major and short oral presentations are now available on-demand. If you were not able to attend the live sessions, you can order and watch them later for 3 weeks. Order now.

Abstracts book of Polyphenols 2024 Congress

2024-09-12T13:09:43+00:00

The Polyphenols Applications 2024 Abstracts Book - containing all 123+ major, short talks and poster presentations - is now available.

The book is assigned with a DOI (Digital Object Identifier). This ensures a permanent and easily accessible online presence for the entire collection of work.

Polyphenols Applications 2024 Posters List

2024-09-11T11:59:14+00:00

More than 123 communications will be presented during Polyphenols Applications 2024, including more than 70 posters. Access full posters list.

Last updated on 12/09/2024

Polyphenols Applications 2024 Congress
September 19-20, 2024 - Milan
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Polyphenols in Oncotherapy: Moving forward from the Bench to Clinical Applications

2024-04-03T22:00:00+00:00

It is a great pleasure to welcome Prof. José M. Estrela, University of Valencia, Spain, to Polyphenols Applications 2024 this September in Milan.

Presentation Topic: Polyphenols in Oncotherapy: Moving forward from the Bench to Clinical Applications.

Prof. Estrela will discuss the latest clinical data in oncotherapy using a combination of modalities including hyperthermia, electromagnetic fields, chemotherapy, and natural polyphenols.

Presentation Key Points

Introduce the role of polyphenols, highlighting their potential as adjunctive therapies to enhance the efficacy of existing treatments.

Discuss the rationale behind combining hyperthermia, electromagnetic fields, chemotherapy, and polyphenols, emphasizing the potential synergistic effects and mechanisms of action.

Summarize preclinical evidence supporting the efficacy of the proposed combination therapy approach, including studies demonstrating tumor regression and enhanced cancer cell death.

Outline the steps needed to translate preclinical findings into clinical applications, including regulatory considerations, clinical trial design, and patient safety assessments.

Acknowledge potential challenges and limitations, such as variability in patient responses, treatment resistance, and the need for personalized treatment approaches.

Explore future directions for research and innovation in polyphenol-based oncotherapy, including the development of novel delivery methods, targeted therapies, and precision medicine approaches.

About José M. Estrela

José M. Estrela is an Associate professor in the Department of Physiology, University of Valencia, Spain. His study interests major on Physiology. In recent years, he has studied several on Cancer, Oncology, Polyphenols, Cancer Therapy, Tumors. He has published more than 103 articles in many journals.

Polyphenols Applications 2024 Congress
September 19-20, 2024 - Milan
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The Potential of Polyphenols in the Context of Senotherapy

2024-04-02T22:00:00+00:00

Dr. Alessandra Gambero, from Pontifical Catholic University of Campinas, Brazil, will be joining the 17th World Congress on Polyphenols Applications 2024 this September in Milan.

She will present her latest research on the Potential of Polyphenols in the Context of Senotherapy.

Learn more about her findings.

Presentation Summary

Cellular senescence is characterized by a stable cell proliferation arrest and the establishment of a secretory phenotype in normal cells in response to intrinsic and extrinsic stimuli.
Cellular senescence is associated with chronological aging and a response to environmental stressors.
Expanded knowledge about the role of senescence in the physiological context and disease processes and development of drugs that can counteract the harmful effects of cellular senescence as a therapeutic target.
Therefore, senotherapeutics can be classified as senolytics drugs that selectively eliminate senescent cells or senostatics (senomorphic) that inhibit, reverse, or prevent aspects associated with cellular senescence.
The most studied option combines dasatinib and quercetin, a natural polyphenol that targets BCL-2 and PI3K/AKT signaling pathways.
The various pharmacological mechanisms described for polyphenols suggest that others may have senotherapeutic effects, which has been the focus of our recent work.

About Alessandra Gambero

Graduated in Biological Sciences from Paulista State University Júlio de Mesquita Filho (1994), Master in Biological Sciences (Pharmacology) from Paulista State University Júlio de Mesquita Filho (1997), PhD in Pharmacology from University of São Paulo (2001), and Post-doctoral at Paul Sabatier University (Toulouse, France). Currently develops projects in the research area of Aging and cellular senescence, Foods with health claims, and Regenerative Medicine and Innovation in Health.

Polyphenols Applications 2024 Congress
September 19-20, 2024 - Milan
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Why Demonstrating the Health Benefits of Polyphenols isn't Easy: Considerations on Experimental Design to Enhance the Impact of Future Polyphenols Research

2024-04-02T10:00:00+00:00

It is a great pleasure to welcome Prof. Daniele Del Rio, University of Parma, Italy, as a keynote speaker at the 17th World Congress on Polyphenols Applications 2024 this September in Milan.

Prof. Del Rio will open the conference with a speech entitled "Why Demonstrating the Health Benefits of Polyphenols isn't Easy: Considerations on Experimental Design to Enhance the Impact of Future Polyphenols Research".

About Daniele Del Rio

Prof. Daniele Del Rio is a Full Professor of Human Nutrition at the Department of Food and Drug and the Head of the School of Advanced Studies on Food and Nutrition at the University of Parma, in Italy. He is also the scientific director of the NNEdPro Global Center for Nutrition and Health and a Visiting Professor at the School of Biomedical Sciences, Ulster University, UK.

He serves as Editor in Chief of the International Journal of Food Sciences and Nutrition (Taylor & Francis). He is a proud Commendatore (Knight Commander) of the Order of Merit of the Italian Republic, and he is proudly growing a team of brilliant scientists.

Polyphenols Applications 2024 Congress
September 19-20, 2024 - Milan
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Coevolutionary Role of Host and Gut Microbiota in Polyphenol Health Effects: Metabotypes and Precision Health

2024-04-02T10:00:00+00:00

It is a great pleasure to welcome Prof. Juan Carlos Espín, Spanish National Research Council, Spain, to Polyphenols Applications 2024 this September in Milan.

Presentation Topic: Coevolutionary Role of Host and Gut Microbiota in Polyphenol Health Effects: Metabotypes and Precision Health.

Presentation Summary

Individuals can be grouped into different metabotypes (metabolic types) based on their gut microbiota's ability to metabolize certain polyphenols, resulting in unique metabolites with varying molecular structures and biological activities. Thus, the effects of certain polyphenols will greatly depend on each individual's gut microbiota. By understanding the microbial ecologies responsible for these metabolic pathways, "precision-health" strategies could be developed to standardize the effects of polyphenols.

About Juan Carlos Espín

Juan Carlos Espín is is a full Research Professor at CEBAS-CSIC (Murcia, Spain). For the past 24 years, his main lines of research have focused on: i) the metabolism and biodistribution of polyphenols in humans, identifying the final responsible actors for biological effects; ii) the use of exosomes to deliver and enhance the biological activity of polyphenols and derived metabolites in systemic tissues; and iii) understanding why some polyphenols do not exert the same effect in all individuals. His research suggests that specific gut microbial ecologies play crucial roles in mediating the observed effects within the context of "precision health".

Juan Carlos has been a "highly-cited" researcher consecutively from 2018 to the present (only 0.1% of researchers worldwide are "highly-cited"). As of March 2024 (according to Scopus), he has an H-index of 85, with 230 JCR publications totaling approximately 23,000 citations, and has led the second highest-earning patent in the history of the CSIC.

Polyphenols Applications 2024 Congress
September 19-20, 2024 - Milan
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Interplay between Polyphenolic Compounds and Biological Rhythms

2024-04-02T09:00:00+00:00

Prof. Begoña Muguerza, from Universitat Rovira i Virgili, Spain, will be joining the 17th World Congress on Polyphenols Applications 2024 this September in Milan.

She will present her latest research on the Interplay between Polyphenolic Compounds and Biological Rhythms.

About Begoña Muguerza

She is a full Professor in the Biochemistry and Biotechnology Department, at the University Rovira I Virgili, Spain. Dr. Muguerza leads the Nutrigenomics Research Group, focusing its research on the study of the molecular mechanism by which food bioactive components, like (poly)phenols, exert health effects on metabolic pathologies. At present she is interested in the study of the interaction of the biological rhythms with the effectiveness of bioactive ingredients.

She has participated continuously in competitive projects, being PI of over 50. Dr. Muguerza is co-author of more than 150 articles in high-impact scientific journals and 15 patents. She has supervised 9 doctoral theses and currently she is mentoring 3 PhD students. In addition, she has also carried out management activities, being Head of the Biochemistry and Biotechnology Department and Coordinator of the Official Master Interuniversity Nutrition and Metabolism. Currently, she is the Coordinator of the Doctoral Programme in Nutrigenomics and Personalized Nutrition.

Polyphenols Applications 2024 Congress
September 19-20, 2024 - Milan
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